Monotonous diets protect against acute colitis in mice: epidemiologic and therapeutic implications

Published Research

Multiple characteristics of industrialization have been proposed to contribute to the global emergence of inflammatory bowel diseases (IBDs: Crohn disease [CD] and ulcerative colitis [UC]). Major changes in eating habits during the past decades and the effectiveness of exclusive enteral nutrition (EEN) in the treatment of CD indicate the etiologic importance of dietary intake in IBDs. A uniform characteristic of nutrition in developing countries (where the incidence of IBD is low) and EEN is their consistent nature over prolonged periods. However, the potentially beneficial effect of dietary monotony in respect to mammalian intestinal inflammation has not been examined.

View PDF